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Participants will initially be asked to attend up to 4 sessions of testing that may take up to 3 hours per session.
**Before each participant comes in for their first session, they will complete an online health history questionnaire and phone screening to check that they are eligible for the study. Testing sessions will be at least 48 hours, and up to 1 week apart.
If a participant currently participates in regular strength and/or power training exercise or has done so on a regular basis in the last 6 months, they will be able to participate in the initial experimental sessions but will not be eligible for the additional exercise training program.
Testing sessions will include the following:
1. Informed consent.
2. DXA body composition scan at the University of Michigan’s School of Kinesiology.
3. Blood pressure measurement.
4. Neuropathy screening.
5. Submaximal cycle aerobic fitness test accompanied with a 12 lead ECG.
6. A finger prick and blood draw to measure blood sugar and blood lipids.
7. Ultrasound measurements of blood vessels in the upper thigh.
8. Temporary blocking of blood flow to the lower leg.
9. Maximal strength testing of the thigh muscles.
10. Stimulation of the thigh muscles.
11. Fatiguing exercise of the lower limb (thigh muscles) while seated.
Interested in Participating?
Please complete our Health History Questionaire.
Once complete the study coordinator will contact you about your eligibility
Participants who qualify, will also be able to participate in a supervised exercise training program of up to 8 weeks (3 times/week) in the laboratory and training rooms in the School of Kinesiology. Participants will be required to attend additional experimental testing sessions after the exercise training program as well as receive MRI scans of their legs before and after training to quantify the size of their leg muscles.
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